AI4Science Tools

Curated collection of models and tools that actually work

Structure Prediction Academic

AlphaFold3

Joint structure prediction of complexes including proteins, nucleic acids, small molecules, and more.

protein structure DeepMind
Website →
Platform Commercial

NVIDIA BioNeMo

Cloud platform for training and deploying biomolecular AI models.

platform enterprise training
Website →
Structure Prediction MIT

Boltz-1

Open-source biomolecular structure prediction model. MIT licensed.

protein structure open-source
Website → GitHub
Structure Prediction Proprietary

Chai-1

Multi-modal foundation model for molecular structure prediction with drug discovery focus.

protein drug-discovery commercial
Website →
Molecular Docking MIT

DiffDock

Diffusion-based molecular docking. State-of-the-art blind docking performance.

docking diffusion drug-discovery
Website → GitHub
Protein Language Model Open (non-commercial)

ESM-3

Multimodal generative model that reasons over sequence, structure, and function.

protein language-model generative
Website → GitHub
Protein Design BSD

RFdiffusion

Diffusion model for de novo protein design from the Baker lab.

protein design diffusion
Website → GitHub
Molecular Representation MIT

UniMol

3D molecular pretraining framework for property prediction and generation.

molecule representation pretraining
Website → GitHub

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